Pasteurella multocida

 Pasteurella multocida :

    • It's gram-negative Bacteria.
    • Non-motile
    • sensitive to penicillium
    • Family Pasteurellaceae
    • Genus Pasteurella
    • 16S rRNA gene



    GRAM NEGATIVE BACTERIUM- INDICATES PINK IN COLOR

    Phylogenic and molecular study of P.multocida :

     The bacterium has 146 KDa protein belonging to the A-B of toxins. nucleotides sequencing of 1.3Kbp and phylogenetic analysis isolates 16s rRNA gene isolates.
     Molecular characterization of P. multocida local strain using Enterobacterial Repetitive Intergenic Consensus (ERIC), 13 virulence genes and the outer membrane protein (OmpH) gene provided data information that could be used as a diagnostic tool, epidemiological markers.
    The serotype A and D of the organism produce a protein toxin PMT  which is responsible for the pathogenesis of virulent factor that causes disease.
     
    IN ANIMALS:
    Pasteurella species are highly prevalent among animal populations, where they are often found as part of the normal microbiota of the oral, nasopharyngeal, and upper respiratory tracts of animals.
    Pasteurella multocida is the cause of diseases in mammals and birds, cholera in poultry, atrophic rhinitis in pigs, and hemorrhagic septicemia in wild and domestic ruminants including cattle, buffalo, sheep, goats, deer and antelope.

     

    IN HUMANS:
    Pasteurella is caused in humans by bites or scratches of dogs and cats. symptoms are edema, erythema, induration, and tenderness at the site of the biting area. It can also cause damage in soft tissue areas if no proper treatment it leads to complicated by abscesses, septic arthritis, and osteomyelitis.

     ANTIBIOTICS TO CONTROL:

     

       Infection is control by antibiotic.


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